barrier icon

The Problem

We have made little progress in treating brain diseases, with the primary culprit being the blood-brain barrier that 1) blocks drugs from getting into the brain and 2) blocks diagnostic biomarkers, stopping measurement through a blood test.

family icon

The Impact

Brain cancers, Alzheimer's Parkinson's, and Epilepsy affect ~10M US patients, each year and growing rapidly.

Cordance icon

Our Vision

We are developing a non-invasive medical device that reversibly opens the blood-brain barrier precisely where it is needed, which will usher in a new wave of diagnostic & therapeutic opportunities for patients.

What is the Blood Brain Barrier

and its relevance to therapy

The blood-brain barrier (BBB) protects the brain from toxins and infectious agents by tightly regulating the passage of chemicals between the circulatory system and the brain. Not only does the BBB prevent most molecules from interacting with brain tissue, but the BBB prevents systemic drugs that could otherwise be effective from reaching the brain.

digital rendering of a brain with a padlock over brain
elderly woman being escorted by young nurse

Improved Efficacy and Patient Access

Non-Invasive, Patient-Friendly

Our NeuroAccess™ medical device will enable precision medicine, the ability to deliver drugs, and measure circulating biomarkers with a blood test to diagnose and track brain diseases by reversibly opening the blood-brain barrier.  We plan to develop applications for patients with brain cancers, Alzheimer's, Parkinson's, and Epilepsy. The device targets the diseased part of the brain and utilizes low-frequency focused ultrasound and microbubbles to mechanically open up the BBB.

Our device has an approved patent and multiple pending patents. The device utilizes focused ultrasound technology, which has been researched by multiple researchers worldwide. Our research makes it possible to enable the broad deployment of the focused ultrasound technology in a patient-friendly and non-invasive manner.

We are a collection of scientists, engineers, clinicians and business leaders.

Coming together to impact one of the greatest healthcare challenges of our generation.