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The Problem

We have made little progress in treating diseases of the brain, with the primary culprit being the blood-brain barrier which blocks drugs from getting into the brain.

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The Impact

Brain cancers, Alzheimer's Parkinson's, and Epilepsy affect ~10M US patients, each year and growing rapidly.

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Our Vision

We are developing a non-invasive medical device which reversibly opens the blood-brain barrier precisely where it is needed which will usher a new wave of therapeutic opportunities for patients.

What is the Blood Brain Barrier

and its relevance to therapy

The blood-brain barrier (BBB) protects the brain from toxins and infectious agents by tightly regulating the passage of chemicals between the circulatory system and the brain. Not only does the BBB prevent most molecules from interacting with brain tissue, but the BBB prevents systemic drugs that could otherwise be effective from reaching the brain.

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Improved Efficacy and Patient Access

Non-Invasive, Patient-Friendly

Our medical device will improve drug delivery to brain diseases by reversibly opening the blood-brain barrier designed for patients with brain cancers, Alzheimer's, Parkinson's and Epilepsy. The device works by targeting the diseased part of the brain and utilizing low-frequency focused ultrasound and microbubbles to mechanically open up the BBB.

Our device has multiple pending patents. The device utilizes focused ultrasound technology which has been researched by multiple researchers across the world. Our research makes it possible to enable broad deployment of the focused ultrasound technology in a patient-friendly and non-invasive manner.

We are a collection of scientists, engineers, clinicians and business leaders.

Coming together to impact one of the greatest healthcare challenges of our generation.